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- Intrinsic LifeSciences has moved locations
- Intrinsic LifeSciences presented at the American Society of Hematology meeting in Orlando
- Intrinsic LifeSciences will be at the 2011 BioIron congress in Vancouver
- Intrinsic LifeSciences awarded a 48D tax credit for 2009 and 2010 Research & Development investments
- Intrinsic LifeSciences is awarded an NIH SBIR Phase 2 grant
- New Patent
- 15 Dec-2009
- 31 Mar-2009
- Intrinsic LifeSciences scientists demonstrate relationship between iron absorption and hepcidin healthy adult women.
- 10 Feb-2009
- 17 Nov-2008
- A new blood test for diseases of iron metabolism
- 08 Dec-2008
- National Anemia Action Council expert reviews and comments on ILS's recent Blood paper (Ganz et al. 2008).
- Intrinsic LifeSciences and the UCLA David Geffen School of Medicine announce the publication of their jointly developed ELISA assay for hepcidin in the journal Blood.
- 08 Aug-2008
- 05 Apr-2008
- 05 Apr-2008
- Intrinsic LifeSciences Sponsoring National Anemia Action Committee
- Hepcidin
- Hepcidin ELISA
- Publications
- Free Full Text Hepcidin Articles
- Hepcidin is involved in iron regulation in the ischemic brain.
- Hepcidin expression in the liver of mice with implanted tumour reacts to iron deficiency, inflammation and erythropoietin administration.
- Iron supplementation in nephrology and oncology: what do we have in common?
- Hepatic HIF-2 down-regulates hepcidin expression in mice through epo-mediated increase in erythropoiesis.
- Antimicrobial Peptides in Innate Immunity against Mycobacteria.
- Fetal iron levels are regulated by maternal and fetal Hfe genotype and dietary iron.
- AG490: An inhibitor of hepcidin expression in vivo.
- Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study.
- BMPER is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice.
- Alcohol Activates TGF-Beta but Inhibits BMP Receptor-Mediated Smad Signaling and Smad4 Binding to Hepcidin Promoter in the Liver.
- Control of systemic iron homeostasis by the hemojuvelin-hepcidin axis.
- Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload.
- Hemojuvelin is essential for transferrin-dependent and -independent hepcidin expression in mice.
- The -582A>G variant of the HAMP promoter is not associated with high serum ferritin levels in normal subjects.
- Accelerated CCl(4)-Induced Liver Fibrosis in Hjv-/- Mice, Associated with an Oxidative Burst and Precocious Profibrogenic Gene Expression.
- Liver and muscle hemojuvelin are differently glycosylated.
- Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies.
- Characterization of the transition-metal-binding properties of hepcidin.
- Anemic copper-deficient rats, but not mice, display low hepcidin expression and high ferroportin levels.
- Increased serum hepcidin and alterations in blood iron parameters associated with asymptomatic P. falciparum and P. vivax malaria.
- Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis.
- Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation.
- Oncostatin M is a potent inducer of hepcidin, the iron regulatory hormone.
- Serum pro-hepcidin could reflect disease activity in patients with rheumatoid arthritis.
- Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD.
- Growth differentiation factor 15 in erythroid health and disease.
- Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues.
- Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.
- Reduction of serum hepcidin by hemodialysis in pediatric and adult patients.
- Increased iron stores correlate with worse disease outcomes in a mouse model of schistosomiasis infection.
- Iron, the retina and the lens: a focused review.
- Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages.
- Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
- Evaluation of hepcidin isoforms in hemodialysis patients by a proteomic approach based on SELDI-TOF MS.
- Alpha 1-acid glycoprotein, hepcidin, C-reactive protein, and serum ferritin are correlated in anemic schoolchildren with Schistosoma haematobium.
- Letter by ryan et Al regarding article, do hemochromatosis mutations protect against iron-mediated atherogenesis? .
- Successful antiviral therapy is associated with a decrease of serum prohepcidin in chronic hepatitis C.
- Unexplained aspects of anemia of inflammation.
- The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
- Advancement of the study on iron metabolism and regulation in tumor cells.
- Severe iron deficiency blunts the response of the iron regulatory gene Hamp and pro-inflammatory cytokines to lipopolysaccharide.
- Neutrophil gelatinase-associated lipocalin and hepcidin: what do they have in common and is there a potential interaction?
- Iron Loading and Overloading due to Ineffective Erythropoiesis.
- Randomized, double-blind, placebo-controlled trial of an iron-fortified food product in female soldiers during military training: relations between iron status, serum hepcidin, and inflammation.
- Presence of hepcidin-25 in biological fluids: bile, ascitic and pleural fluids.
- Iron homeostasis and the inflammatory response.
- Specific hemosiderin deposition in spleen induced by a low dose of cisplatin: altered iron metabolism and its implication as an acute hemosiderin formation model.
- The iron driven pathway of hepcidin synthesis.
- Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice.
- Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2- and BMP6-mediated signaling and gene expression.
- Serum prohepcidin levels in Helicobacter pylori infected patients with iron deficiency anemia.
- Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.
- Crosstalk between Iron Metabolism and Erythropoiesis.
- A close association of abnormal iron metabolism with steatosis in the mice fed a choline-deficient diet.
- Transferrin receptor 2 is crucial for iron sensing in human hepatocytes.
- Suppression of SLC11A2 expression is essential to maintain duodenal integrity during dietary iron overload.
- Immunoassay for human serum hemojuvelin.
- Hepcidin in beta-thalassemia.
- A novel TMPRSS6 mutation that prevents protease auto-activation causes IRIDA.
- Increased susceptibility to iron deficiency of Tmprss6-haploinsufficient mice.
- Multiple regulatory mechanisms act in concert to control ferroportin expression and heme iron recycling by macrophages.
- Hepcidin levels in hereditary hyperferritinemia: Insights into the iron-sensing mechanism in hepatocytes.
- Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice.
- Benefits and risks of iron supplementation in anemic neonatal pigs.
- Hepatic but not brain iron is rapidly chelated by deferasirox in aceruloplasminemia due to a novel gene mutation.
- Pharmacokinetics of anti-hepcidin monoclonal antibody Ab 12B9m and hepcidin in cynomolgus monkeys.
- Current status of the measurement of blood hepcidin levels in chronic kidney disease.
- Iron status, inflammation and hepcidin in ESRD patients: The confounding role of intravenous iron therapy.
- Ferroportin and hepcidin: a new hope in diagnosis, prognosis, and therapy for breast cancer.
- Aqueous humor hepcidin prohormone levels in patients with primary open angle glaucoma.
- Analysis of nucleotide variations in genes of iron management in patients of Parkinson's disease and other movement disorders.
- Iron overload induces BMP6 expression in the liver but not in the duodenum.
- Serum prohepcidin levels in chronic hepatitis C, alcoholic liver disease, and nonalcoholic fatty liver disease.
- Importance of ferritin for optimizing anemia therapy in chronic kidney disease.
- Genetic study of the hepcidin gene (HAMP) promoter and functional analysis of the c.-582A > G variant.
- Increased hepcidin-25 and erythropoietin responsiveness in patients with cardio-renal anemia syndrome.
- Hepcidin induces HIV-1 transcription inhibited by ferroportin.
- Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.
- A tincture of hepcidin cures all: the potential for hepcidin therapeutics.
- Hemojuvelin and hepcidin gene mutations in patients with porphyria cutanea tarda from Southern France.
- Patients with chronic hepatitis C may be more sensitive to iron hepatotoxicity than patients with HFE-hemochromatosis.
- Hepcidin biology and therapeutic applications.
- Hepcidin: the main regulator of iron homeostasis.
- ER Stress and Iron Homeostasis: A New Frontier for the UPR.
- Hepcidin and iron species distribution inside the first-trimester human gestational sac.
- A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis.
- Gender-related variations in iron metabolism and liver diseases.
- Hepcidin as a biochemical parameter for the assessment of iron deficiency anemia.
- The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice.
- Iron bioavailibity from a tropical leafy vegetable in anaemic mice.
- BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin.
- Hepcidin is an antibacterial, stress-inducible peptide of the biliary system.
- Hepcidin and anemia of the critically ill patient: bench to bedside.
- Anemia of inflammation.
- Anemia in elderly patients: an emerging problem for the 21st century.
- Some aspects of the anemia of chronic disorders modeled and analyzed by petri net based approach.
- Mass spectrometry analysis of hepcidin peptides in experimental mouse models.
- Differential HFE gene expression is regulated by alternative splicing in human tissues.
- Plasma hepcidin correlates positively with interleukin-6 in patients undergoing pulmonary endarterectomy.
- Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
- Iron regulation by hepatocytes and free radicals.
- Novel observations in hereditary hemochromatosis: potential implications for clinical strategies.
- Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response.
- Hepcidin expression in human airway epithelial cells is regulated by interferon-γ.
- Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: A case control study.
- Proteomic biomarkers apolipoprotein A1, truncated transthyretin and connective tissue activating protein III enhance the sensitivity of CA125 for detecting early stage epithelial ovarian cancer.
- Highly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?
- Prospects for a hepcidin mimic to treat β-thalassemia and hemochromatosis.
- Hepcidin levels and their determinants in different types of myelodysplastic syndromes.
- Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo.
- Urinary hepcidin level as an early predictor of iron deficiency in children: A case control study.
- Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice.
- Full Text Hepcidin Articles
- Effect of different iron loads on serum and tissue biochemical parameters and liver hepcidin mRNA abundance of neonatal piglets.
- Plasma hepcidin correlates positively with interleukin-6 in patients undergoing pulmonary endarterectomy.
- Friend of GATA suppresses the GATA-induced transcription of hepcidin in hepatocytes through a GATA-regulatory element in the HAMP promoter.
- Advancement of the study on iron metabolism and regulation in tumor cells.
- Hepcidin is regulated during blood-stage malaria and plays a protective role in malaria infection.
- The role of catalytic iron in acute kidney injury.
- Hepcidin and iron homeostasis.
- Murine mutants in the study of systemic iron metabolism and its disorders: An update on recent advances.
- Effects of iron supplementation on serum hepcidin and serum erythropoietin in low-birth-weight infants.
- Natural history and management of HFE-hemochromatosis.
- Closing the iron gate.
- Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload.
- IL-6 is an independent risk factor for resistance to erythropoiesis-stimulating agents in hemodialysis patients without iron deficiency.
- Hepcidin Concentrations in Serum and Urine Correlate with Iron Homeostasis in Preterm Infants.
- Role of hepcidin in iron metabolism and potential clinical applications.
- Hepcidin and hemoglobin content parameters in the diagnosis of iron deficiency in rheumatoid arthritis patients with anemia.
- Iron deficiency in critically ill patients: highlighting the role of hepcidin.
- Hepcidin in malaria superinfection: can findings be translated to humans?
- Hepcidin in human iron disorders: diagnostic implications.
- Iron supplementation in nephrology and oncology: what do we have in common?
- Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6.
- Hemojuvelin: a new link between obesity and iron homeostasis.
- Downregulation of Ferroportin 1 Expression in hFOB1.19 Osteoblasts by Hepcidin.
- Regulation of iron metabolism in Hamp (-/-) mice in response to iron-deficient diet.
- Maternal quercetin intake during pregnancy results in an adapted iron homeostasis at adulthood.
- The role of erythropoiesis stimulating agents and intravenous (IV) iron in the cardio renal anemia syndrome.
- Hepatic HIF-2 down-regulates hepcidin expression in mice through epo-mediated increase in erythropoiesis.
- Liver and muscle hemojuvelin are differently glycosylated.
- Cardioprotection by Hepc1 in cTnT(R141W) transgenic mice.
- Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase-1 deficiency.
- Hepcidin as well as TNF-α are significant predictors of arterial stiffness in patients on maintenance hemodialysis.
- Serum ferritin levels are associated with vascular damage in patients with nonalcoholic fatty liver disease.
- AG490: An inhibitor of hepcidin expression in vivo.
- The acute phase response of cod (Gadus morhua L.): Expression of immune response genes.
- Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study.
- Mycobacterium tuberculosis components stimulate production of the antimicrobial peptide hepcidin.
- Serum levels of hepcidin in patients with biopsy-proven nonalcoholic fatty liver disease.
- Inactivation of prolyl hydroxylase domain (PHD) protein by epigallocatechin (EGCG) stabilizes hypoxia-inducible factor (HIF-1α) and induces hepcidin (Hamp) in rat kidney.
- Regulation of hepcidin expression at high altitude.
- Is hemojuvelin a possible new player in iron metabolism in hemodialysis patients?
- Safety and efficacy of iron supplements in malaria-endemic areas.
- Alcohol Activates TGF-Beta but Inhibits BMP Receptor-Mediated Smad Signaling and Smad4 Binding to Hepcidin Promoter in the Liver.
- Maternal Hepcidin Is Associated with Placental Transfer of Iron Derived from Dietary Heme and Nonheme Sources.
- Control of immunopathology during Plasmodium infection by hepcidin.
- Pharmacological Suppression of Hepcidin Increases Macrophage Cholesterol Efflux and Reduces Foam Cell Formation and Atherosclerosis.
- A novel Y231del mutation of HFE in hereditary haemochromatosis provides in vivo evidence that the Huh-7 is a human haemochromatotic cell line.
- Hepatic acute phase proteins - Regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling.
- Regulation of iron transport and the role of transferrin.
- Hepcidin as a biochemical parameter for the assessment of iron deficiency anemia.
- Development of a nano-liquid chromatography on chip tandem mass spectrometry method for high-sensitivity hepcidin quantitation.
- Can erythroblasts donate iron?
- Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response.
- Hepcidin expression in patients with acute leukaemia.
- Iron sensing and signalling.
- Fungicidal activity of the human peptide hepcidin 20 alone or in combination with other antifungals against Candida glabrata isolates.
- Impact of dialysis technique on renal anemia.
- Hematological and acute-phase responses to diet-induced obesity in IL-6 KO mice.
- [GDF15 expression and iron overload in ineffective erythropoiesis].
- [Signaling in iron metabolism via transferrin receptor 2: significance in erythropoiesis].
- Expressed sequence tags (ESTs) based identification of genes and expression analysis of leukocyte cell-derived chemotaxin-2 (LECT2) from Epinephelus bruneus.
- The relationship between obesity and hypoferraemia in adults: a systematic review.
- Adipocyte hypoxia increases hepatocyte hepcidin expression.
- The -582A>G variant of the HAMP promoter is not associated with high serum ferritin levels in normal subjects.
- Accelerated CCl(4)-Induced Liver Fibrosis in Hjv-/- Mice, Associated with an Oxidative Burst and Precocious Profibrogenic Gene Expression.
- Some aspects of the anemia of chronic disorders modeled and analyzed by petri net based approach.
- Iron overload induces BMP6 expression in the liver but not in the duodenum.
- Molecular characterization of hepcidin gene from mud loach (Misgurnus mizolepis; Cypriniformes).
- Design and validation of a novel high-throughput Matrix-Assisted Laser Desorption Ionization Time-of-Flight mass spectrometry method for quantification of hepcidin in human plasma.
- Hepcidin is involved in iron regulation in the ischemic brain.
- Formula Feeding Alters Hepatic Gene Expression Signature, Iron and Cholesterol Homeostasis in the Neonatal Pig.
- Dissociation of ferritin and hepcidin in a case of adult-onset Still's disease.
- Differential immune response of rainbow trout (Oncorhynchus mykiss) at early developmental stages (larvae and fry) against the bacterial pathogen Yersinia ruckeri.
- Iron-mediated retinal degeneration in hemojuvelin knockout mice.
- Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice.
- Hereditary hemochromatosis: mutations in genes involved in iron homeostasis in Brazilian patients.
- Thalassemia intermedia is associated with a proatherogenic biochemical phenotype.
- Diagnosing anemia in inflammatory bowel disease: Beyond the established markers.
- Lipopolysaccharide infusion up-regulates hepcidin mRNA expression in equine liver.
- Modification of hepatic iron metabolism induced by pravastatin during obstructive cholestasis in rats.
- The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels.
- Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.
- Liver and serum iron: discrete regulators of hepatic hepcidin expression.
- A novel mutation Gly603Arg of TMPRSS6 in a Korean female with iron-refractory iron deficiency anemia.
- Diagnosis and management of anaemia of chronic disease: current status.
- GATA-4 transcription factor regulates hepatic hepcidin expression.
- Mycobacteria-induced anaemia revisited: A molecular approach reveals the involvement of NRAMP1 and lipocalin-2, but not of hepcidin.
- Modulation of hepatitis C virus replication by iron and hepcidin in Huh7 hepatocytes.
- Evidence for a proatherogenic biochemical phenotype in Beta thalassemia minor and intermedia.
- Hemoglobin and iron indices in nonanemic premenopausal blood donors predict future deferral from whole blood donation.
- Host-mediated regulation of superinfection in malaria.
- Restless legs syndrome is associated with irritable bowel syndrome and small intestinal bacterial overgrowth.
- Alterations in lipid, carbohydrate and iron metabolism in patients with non-alcoholic steatohepatitis (NASH) and metabolic syndrome.
- Reduced expression of ferroportin-1 mediates hyporesponsiveness of suckling rats to stimuli that reduce iron absorption.
- Knockout mouse models of iron homeostasis.
- Erythropoietin, GDF15, IL6, hepcidin and testosterone levels in a large cohort of elderly individuals with anaemia of known and unknown cause.
- Serum hepcidin: reference ranges and biochemical correlates in the general population.
- The hepcidin circuits act: balancing iron and inflammation.
- Hepcidin expression and iron parameters change in Type 2 diabetic patients.
- Hereditary hemochromatosis: laboratory evaluation.
- Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors.
- Increased expression of hepcidin and toll-like receptors 8 and 10 in viral keratitis.
- Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis.
- Bioactivity studies of rainbow trout (Oncorhynchus mykiss) interleukin-6: Effects on macrophage growth and antimicrobial peptide gene expression.
- Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.
- Integrative assessment of potential effects of dioxins and related compounds in wild Baikal seals (Pusa sibirica): application of microarray and biochemical analyses.
- Hemochromatosis, HFE C282Y Homozygosity, and Polycystic Ovary Syndrome: Report of Two Cases and Possible Effects of Androgens and Hepcidin.
- Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts.
- Effect of diquat-induced oxidative stress on iron metabolism in male Fischer-344 rats.
- Highly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?
- Nuclear factor-kB mediated lipopolysaccharide-induced mRNA expression of hepcidin in human peripheral blood leukocytes.
- New rat models of iron sucrose-induced iron overload.
- The marine medaka Oryzias melastigma--a potential marine fish model for innate immune study.
- Limiting iron supplementation for anemia in dialysis patients--the Basis for Japan's conservative guidelines.
- Hepcidin: clinical utility as a diagnostic tool and therapeutic target.
- Two hepcidin-like antimicrobial peptides in Barramundi Lates calcarifer exhibit differing tissue tropism and are induced in response to lipopolysaccharide.
- Treatment of chronic periodontitis decreases serum prohepcidin levels in patients with chronic kidney disease.
- Blunted increase in serum hepcidin as response to oral iron in HFE-hemochromatosis.
- Reproducibility of and correspondence among different hepcidin forms in blood and urine and their relationships to iron status in healthy, male Guatemalan volunteers observed over 9 weeks.
- Gastrin-deficient mice have disturbed hematopoiesis in response to iron deficiency.
- Novel missense mutation in the TMPRSS6 gene in a Japanese female with iron-refractory iron deficiency anemia.
- Transgenic expression of tilapia hepcidin 1-5 and shrimp chelonianin in zebrafish and their resistance to bacterial pathogens.
- Low hepcidin accounts for the proinflammatory status associated with iron deficiency.
- Case studies: iron.
- Hepcidin response to acute iron intake and chronic iron loading in dysmetabolic iron overload syndrome.
- Serum maternal hepcidin levels 3 days after delivery are higher compared to those measured at parturition.
- Pharmacologic inhibition of hepcidin expression reverses anemia of chronic disease in rats.
- Modulation of the immune-related gene responses to protect mice against Japanese encephalitis virus using the antimicrobial peptide, tilapia hepcidin 1-5.
- Essential Role of Endocytosis of the Type II Transmembrane Serine Protease TMPRSS6 in Regulating Its Functionality.
- Optimization of micro-HPLC peak focusing for the detection and quantification of low hepcidin concentrations.
- Proteomic biomarkers in combination with CA 125 for detection of epithelial ovarian cancer using prediagnostic serum samples from the prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial.
- Renal Anemia of Inflammation: The Name Is Self-Explanatory.
- Early effects of erythropoietin on serum hepcidin and serum iron bioavailability in healthy volunteers.
- Altered Lipid Metabolism in Hfe-Knockout Mice Promotes Severe NAFLD and Early Fibrosis.
- Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury - an observational cohort study.
- Erythrocyte pyruvate kinase deficiency in an old-order Amish cohort: Longitudinal risk and disease management.
- Hepcidin expression in human airway epithelial cells is regulated by interferon-γ.
- Determinants of red cell distribution width (RDW) in cardiorenal patients: RDW is not related to erythropoietin resistance.
- Greater increase in urinary hepcidin predicts protection from acute kidney injury after cardiopulmonary bypass.
- Serum hepcidin-25 levels and anemia in non-dialysis chronic kidney disease patients: a cross-sectional study.
- Molecular mechanisms regulating hepcidin revealed by hepcidin disorders.
- Iron and intestinal immunity.
- Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver.
- Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.
- Hepcidin: another culprit for complications in patients with chronic kidney disease?
- -thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.
- Hepcidin and disordered mineral metabolism in chronic kidney disease.
- The immune response of turbot, Scophthalmus maximus (L.), skin to high water temperature.
- Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection.
- Insights into the antibacterial and immunomodulatory functions of tilapia hepcidin (TH)2-3 against Vibrio vulnificus infection in mice.
- Conditional disruption of mouse Hfe2 gene: Maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.
- Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.
- Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights.
- Hepcidin expression in the liver of rats fed a magnesium-deficient diet.
- Hepcidin increases intracellular Ca(2+) of osteoblast hFOB1.19 through L-type Ca(2+) channels.
- Non-HFE Hepatic Iron Overload.
- The molecular pathogenesis of hereditary hemochromatosis.
- Hepcidin and ferroportin: the new players in iron metabolism.
- Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice.
- Hepcidin levels and their determinants in different types of myelodysplastic syndromes.
- Urinary Hepcidin-25 and Risk of Acute Kidney Injury Following Cardiopulmonary Bypass.
- Serum Hepcidin: A Direct Link Between Anemia of Inflammation and Coronary Artery Atherosclerosis in Patients with Rheumatoid Arthritis.
- Hepcidin and iron-mediated resistance to malaria.
- Chuvash polycythemia VHLR200W mutation is associated with downregulation of hepcidin expression.
- TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals.
- Hepcidin regulation by innate immune and infectious stimuli.
- Effects of a single dose of oral iron on hepcidin concentrations in human urine and serum analyzed by a robust LC-MS/MS method.
- Hereditary hemochromatosis and transferrin receptor 2.
- Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma.
- Iron disorders of genetic origin: a changing world.
- A novel proteomic biomarker panel as a diagnostic tool for patients with ovarian cancer.
- Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice.
- Posttransplantation anemia: relationship with inflammatory markers, oxidation, and prohepcidin levels.
- Synthesis and Biological Activity of Mouse Hepcidin Peptide Analogs Containing Three Disulfide Bridges: Manual and Microwave-Assisted Solid-Phase Peptide Synthesis.
- Hepcidin: A Critical Regulator of Iron Metabolism during Hypoxia.
- Free Full Text Hepcidin Articles
- Hepcidin Assay Info
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