Mark Westerman founded Intrinsic LifeSciences (ILS) in 2006 along with Drs. Tomas Ganz and Elizabeta Nemeth, and has served as President & CEO since. After postdoctoral research at Scripps Institution of Oceanography and as a National Research Council Fellow to NOAA, he built and directed an internationally recognized marine biotechnology program focused on advanced vaccine and diagnostics technologies.
Dr. Westerman and his corporate and academic colleagues discovered and characterized bass hepcidin soon after its discovery in humans by Tomas Ganz (UCLA, David Geffen School of Medicine). He was instrumental in development of a novel serum hepcidin ELISA and was awarded two patents related to the company’s products. Dr. Westerman has authored two patent applications in prosecution and over 25 peer reviewed scientific articles, and serves as an Editorial Board Member of Marine Biotechnology. He holds a Masters degree from the University of Texas at Austin and a Ph.D. from Texas A&M University.
Mark Westerman’s Selected Publications:
- • Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors.
- • Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project.
- • Hepcidin in trauma: linking injury, inflammation, and anemia.
- • Urinary hepcidin: an inverse biomarker of acute kidney injury after cardiopulmonary bypass?
- • Hepcidin–a potential novel biomarker for iron status in chronic kidney disease.
- • Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women.
- • Immunoassay for human serum hepcidin.
- • A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron.
- • Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections.
- • Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge.
For the full list of publications, click here http://www.ncbi.nlm.nih.gov/pubmed?term=hepcidin%20OR%20la%20jolla%20OR%20college%20station%20AND%20westerman%20m