Intrinsic Erythroferrone IE™ ELISA Kit

Description

The Intrinsic ERFE IETM ELISA is a test kit designed for quantification of human Erythroferrone in serum. This kit does not contain mercaptoethanol, azide- or mercury-based preservatives.

Erythroferrone (ERFE) is a hormone produced by erythroblasts in the bone marrow in response to erythropoietin. Recent animal studies have shown that ERFE acts as a stress erythropoiesis-specific regulator of hepcidin expression. By suppressing hepcidin expression in the liver, ERFE contributes to increased dietary iron absorption and recycling of stored iron necessary for recovery of blood loss due to hemorrhage or phlebotomy. In addition, ERFE was found to be involved in hepcidin regulation in inherited iron loading anemias, such as beta-Thalassemia. ERFE has potential as a clinical marker for assessing erythropoiesis in patients with blood disorders.

Patents Pending in the US and abroad.

ERF-001 Product Insert v1

Questions? Please email us: custserv@intrinsiclifesciences.com

SKU: ERF-001 Category: Tags: , , , , , , ,

$888.00

Quantity
96 Tests (1x96 well)
Application
ELISA
Method
Sandwich
Antibody Type
Monoclonal
Target Species
Human
Analyte
Erythroferrone (ERFE) / Myonectin / FAM132B / CTRP15 / C1QTNF15
Sample Type
Serum
Recommended Sample Volume
10 μl
Standard Range
0.16 - 10 ng/ml
Regulatory Status
Research Use Only. Not for use in diagnostic procedures.
Stability
3 months from date of shipment. Each kit is assembled prior to shipment and assigned an expiration date.
Storage Requirements
2 - 8 C
Shipping Condition
Ambient

Description

The Intrinsic ERFE IETM ELISA is a test kit designed for quantification of human Erythroferrone in serum. This kit does not contain mercaptoethanol, azide- or mercury-based preservatives.

Erythroferrone (ERFE) is a hormone produced by erythroblasts in the bone marrow in response to erythropoietin. Recent animal studies have shown that ERFE acts as a stress erythropoiesis-specific regulator of hepcidin expression. By suppressing hepcidin expression in the liver, ERFE contributes to increased dietary iron absorption and recycling of stored iron necessary for recovery of blood loss due to hemorrhage or phlebotomy. In addition, ERFE was found to be involved in hepcidin regulation in inherited iron loading anemias, such as beta-Thalassemia. ERFE has potential as a clinical marker for assessing erythropoiesis in patients with blood disorders.

Patents Pending in the US and abroad.

ERF-001 Product Insert v1

Questions? Please email us: custserv@intrinsiclifesciences.com

Additional information

Weight 10 oz
Dimensions 7 x 7 x 4 in
0

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