Primate-Hepcidin Compete™ ELISA Kit

Description

The Intrinsic LifeSciences Primate-Hepcidin CompeteTM competitive ELISA is designed for quantification of hepcidin-25 in baboon or cynomolgus monkey serum. Quantification of hepcidin-25 from other primate species or from plasma or other body fluids has not been evaluated. This kit does not contain mercaptoethanol, azide- or mercury-based preservatives.

Hepcidin was discovered to be an antimicrobial peptide produced in the liver and is the peptide hormone that regulates extracellular iron in response to changes in dietary and systemic iron load. Hepcidin also regulates iron in response to anemia, hypoxia, erythropoiesis, and inflammation. Hepcidin is an acute phase protein that is elevated in anemia of inflammation. IL-6 is a principal regulator of hepcidin during inflammation. Hepcidin inhibits cellular iron efflux by binding to and inducing degradation of the sole known iron channel, ferroportin. Hepcidin is the master regulator of iron homeostasis in all vertebrates.

U.S. Pat. No. 9,657,098; NZ Pat. No. 631098; Pat. Pending in the US and abroad

PHC-001 Product Insert v3

Questions? Please email us: custserv@intrinsiclifesciences.com

SKU: PHC-001 Category:

$738.00

Quantity
96 Tests (1x96 well)
Application
ELISA
Method
Competitive
Antibody Type
Monoclonal
Target Species
Primate
Analyte
Hepcidin-25
Sample Type
Baboon or cynomolgus monkey serum
Recommended Sample Volume
10 μl
Standard Range
0.55 - 400 ng/ml
Regulatory Status
Research Use Only. Not for use in diagnostic procedures.
Storage Requirements
2 - 8 C
Shipping Condition
Ambient

Description

The Intrinsic LifeSciences Primate-Hepcidin CompeteTM competitive ELISA is designed for quantification of hepcidin-25 in baboon or cynomolgus monkey serum. Quantification of hepcidin-25 from other primate species or from plasma or other body fluids has not been evaluated. This kit does not contain mercaptoethanol, azide- or mercury-based preservatives.

Hepcidin was discovered to be an antimicrobial peptide produced in the liver and is the peptide hormone that regulates extracellular iron in response to changes in dietary and systemic iron load. Hepcidin also regulates iron in response to anemia, hypoxia, erythropoiesis, and inflammation. Hepcidin is an acute phase protein that is elevated in anemia of inflammation. IL-6 is a principal regulator of hepcidin during inflammation. Hepcidin inhibits cellular iron efflux by binding to and inducing degradation of the sole known iron channel, ferroportin. Hepcidin is the master regulator of iron homeostasis in all vertebrates.

U.S. Pat. No. 9,657,098; NZ Pat. No. 631098; Pat. Pending in the US and abroad

PHC-001 Product Insert v3

Questions? Please email us: custserv@intrinsiclifesciences.com

Additional information

Weight 10 oz
Dimensions 7.0 x 6.0 x 4.0 in

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